Physician Profile

Carl Malchoff, M.D., Ph.D.

Professor of Medicine
Office Locations:

Endocrine Neoplasia
Neag Comprehensive Cancer Center
UConn Health
263 Farmington Avenue
Farmington, CT 06030

UConn Health
Outpatient Pavilion, 2nd Floor East
263 Farmington Avenue
Farmington, CT 06030

Board Certifications:
  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
Education and Training:
Undergraduate SchoolCornell UniversityBiological Sciences
Medical SchoolUniversity of Rochester School of Medicine and DentistryMedicine and Biochemistry
FellowshipUniversity of Virginia Medical CenterEndocrinology and Metabolism
InternshipUniversity of Virginia Medical CenterInternal Medicine
ResidencyUniversity of Virginia Medical CenterInternal Medicine
Honors and Awards:
Name of Award/HonorAwarding Organization
Invited Lecture New Guidelines for Surgery for Asymptomatic Primary Hyperparathyroidism,Second Annual New England Endocrine Tumor Symposium at Yale
2012-2013 Best DoctorsUS News and World Report
2012-2013 Best DoctorsUS News and World Report
Honoree of the Raynbow Diabetes Foundation for Contributions to Diabetes Care and ResearchRaynbow Diabetes Foundation
Invited Lecture, Familial Nonmedullary Thyroid CarcinomaAmerican Thyroid Association
Invited Lecture, Adrenal Insufficiency: The Annual Meeting of the Endocrine Nurses SocietyEndocrine Nurses Society
Invited Lecture, Diagnosis of Adrenal Insufficiency: The Endocrine Society 85th Annual MeetingEndocrine Society 85th Annual Meeting
Included in Best Doctors in America Database
Invited Lecture, Molecular Genetics of Familial Papillary Thyroid CarcinomaEndocrine Society Annual Meeting
Invited Lecture, Glucocorticoid Use and Withdrawal,Continuing Education ProgramEndocrine Society
Invited Lecture, Familial Papillary Thyroid CarcinomaSatellite Meeting of the American Society of Human Genetics
Invited Lecture, Adrenal Insufficiency, Continuing Education UpdateEndocrine Society
Leader, Meet the Professor Session - Adrenal InsufficiencyEndocrine Society Annual Meeting
Moderator, Adrenal SessionEndocrine Society Annual Meeting
Invited Lecture, Glucocorticoid ResistanceEndocrine Society, Continuing Education Update
Moderator, Adrenal DisordersEndocrine Society Annual Meeting
Invited "State-of-the-Art" Lecture on Generalized Inherited Glucocorticoid Resistance20th Annual International Aldosterone Conference
Invited Lecture, Generalize Inherited Glucocorticoid ResistanceEndocrine Society Annual Meeting
Moderator, Adrenal Gland Slide Presentation SessionEndocrine Society Annual Meeting
John Horsley Memorial AwardUniversity of Virgina Health Sciences Center
Primary Opponent to Claes-Hakan Bergh, at His Ph.D. Thesis DefenseUniversity of Gothenburg
American Cancer Society Postdoctoral FellowshipAmerican Cancer Society
Young Investigator AwardAmerican Diabetes Association
Juvenile Diabetes Foundation Postdoctoral FellowshipJuvenile Diabetes Foundation
Hospital Affiliation:
  • John Dempsey Hospital
Research Interests:

Dr. Malchoff has a general interest in the molecular pathogenesis of tumors of the thyroid, adrenal, and pituitary gland. Specific research interests include familial papillary thyroid carcinoma, autoimmunity in thyroid cancer, and primary aldosteronism. He has published over 45 peer-reviewed manuscripts and over 35 invited reviews.

Selected Publications:

Peer Reviewed Publications

Glucocorticoid Receptors, Their Mechanisms of Actin , and Glucocorticoid Resistance. Cidlowski J, Malchoff CD, Malchoff D. (2016). Endocrinology: Adult and Pediatric, 1717-1726.

Thyroid Nodules and Shear Wave Elastography: A New Tool in Thyroid Cancer Detection. Azizi, Ghobad; Keller, James M; Mayo, Michelle L; Piper, Kelé; Puett, David; Earp, Karly M; Malchoff, Carl D. (2015). Ultrasound in medicine & biology,

Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice. Xekouki, Paraskevi; Szarek, Eva; Bullova, Petra; Giubellino, Alessio; Quezado, Martha; Mastroyannis, Spyridon A; Mastorakos, Panagiotis; Wassif, Christopher A; Raygada, Margarita; Rentia, Nadia; Dye, Louis; Cougnoux, Antony; Koziol, Deloris; Sierra, Maria de La Luz; Lyssikatos, Charalampos; Belyavskaya, Elena; Malchoff, Carl; Moline, Jessica; Eng, Charis; Maher, Louis James; Pacak, Karel; Lodish, Maya; Stratakis, Constantine A. (2015). The Journal of clinical endocrinology and metabolism, 5, (100), E710-9.

Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas. Cromer, M Kyle; Choi, Murim; Nelson-Williams, Carol; Fonseca, Annabelle L; Kunstman, John W; Korah, Reju M; Overton, John D; Mane, Shrikant; Kenney, Barton; Malchoff, Carl D; Stalberg, Peter; Akerström, Göran; Westin, Gunnar; Hellman, Per; Carling, Tobias; Björklund, Peyman; Lifton, Richard P. (2015). Proceedings of the National Academy of Sciences of the United States of America, 13, (112), 4062-7.

Thyroid hormones and functional outcomes after ischemic stroke. O'Keefe, Lena M; Conway, Sarah E; Czap, Alexandra; Malchoff, Carl D; Benashski, Sharon; Fortunato, Gilbert; Staff, Ilene; McCullough, Louise D. (2015). Thyroid research, (8), 9.