Physician Profile

Isaac L. Moss, M.D., M.A.Sc., FRCSC

Assistant Professor of Orthopaedic Surgery
Comprehensive Spine Center, UConn Musculoskeletal Institute
Assistant Resident Education Director

Dr. Moss is a fellowship trained spine surgeon and assistant professor in the Department of Orthopaedic Surgery and the Comprehensive Spine Center at the UConn Musculoskeletal Institute. Dr. Moss completed residency training in the renowned University of Toronto orthopaedic program, where he was awarded the Lawson Family Post Graduate Fellowship as the department’s top graduate.After completion of his residency, Dr. Moss received specialized training in advanced spinal and scoliosis surgery at Rush University Medical Center in Chicago, where he developed expertise in treating a variety of complex spinal disorders under the guidance of internationally recognized surgeons.

Dr. Moss’ clinical focus is on the treatment of all disorders of the neck and back. He has specific interest in conditions related to both spinal degeneration and deformity. He has extensive experience in minimally invasive surgery (MIS) solutions to many spinal ailments.

Dr. Moss has a master’s degree in biomedical engineering. He has been recognized with several awards and scholarships for his involvement in cutting edge research to develop novel biologic therapies for intervertebral disc degeneration. He is a member of the North American Spine Society and the Orthopaedic Research Society.

Office Locations:

Comprehensive Spine Center
UConn Health
Outpatient Pavilion, 3rd Floor West
263 Farmington Avenue
Farmington, CT 06030-8032

Orthopaedic Surgery
1115 West Street
Southington, CT 06489

Board Certifications:
  • Orthopaedic Surgery
Education and Training:
Undergraduate SchoolDawson CollegeHealth Science (First Choice Program)
Medical SchoolMcGill UniversityMedicine
Graduate SchoolUniversity of TorontoApplied Science
Medical SchoolRoyal College of Physicians and Surgeons of CanadaClinician Investigator Program
ResidencyUniversity of TorontoOrthopaedic Surgery
FellowshipRush University Medical CenterSpine Surgery
Honors and Awards:
Name of Award/HonorAwarding Organization
Lawson Family Post Graduate FellowshipsUniversity of Toronto
R.I. Harris AwardUniversity of Toronto
Top Scoring PostersCanadian Orthopedic Association Annual Meeting
T.R. Sullivan AwardUniversity of Toronto
Gallie Bateman AwardDepartment of Surgery University of Toronto
Canada Graduate Scholarship Masters AwardCanadian Institute of Health Research
J.A. Nutter AwardCanadian Orthopaedic Resident Association
Research ScholarshipAdvanced Regenerative Tissue Engineering Centre
Surgeon Scientist Fellowship Research 2006-2008Draxis Health
Ontario Graduate ScholarshipGovernment of Ontario
J.W. McConnell AwardMcGill University
Dean's Honours ListMcGill Faculty of Medicineip Research
Glaxo Wellcome AwardMcGill Faculty of Medicineip Researchps
Dean's Honour's List 1996-1998Dawson College
Hospital Affiliation:
  • UConn John Dempsey Hospital
Research Interests:

Clinical Research
Evaluating the efficacy and clinical outcomes of spinal surgical techniques including both well-established and novel decompression and fusion strategies.

Basic Science Research
Tissue engineering of the intervertebral disc with an eventual goal to develop a biologic regenerative treatment for degenerative disc disease.

Languages Other than English:
  • French
Selected Publications:

Peer Reviewed Publications

PDGF-BB Delays Degeneration of the Intervertebral Discs in a Rabbit Preclinical Model. Paglia, David N; Singh, Hardeep; Karukonda, Teja; Drissi, Hicham; Moss, Isaac L. (2016). Spine, 8, (41), E449-58.

The Relationship between Preoperative Expectations and the Short-Term Postoperative Satisfaction and Functional Outcome in Lumbar Spine Surgery: A Systematic Review. Ellis, Daniel J; Mallozzi, Scott S; Mathews, Jacob E; Moss, Isaac L; Ouellet, Jean A; Jarzem, Peter; Weber, Michael H. (2015). Global spine journal, 5, (5), 436-52.

Intradural calcifying pseudoneoplasm. Singh, Hardeep; Zengou, Ryan; Moss, Isaac L. (2015). The spine journal : official journal of the North American Spine Society,

Allogeneic Articular Chondrocyte Transplantation Downregulates Interleukin 8 Gene Expression in the Degenerating Rabbit Intervertebral Disk In Vivo. Zhang, Yejia; Chee, Ana; Shi, Peng; Wang, Rui; Moss, Isaac; Chen, Er-Yun; He, Tong-Chuan; An, Howard S. (2014). American journal of physical medicine & rehabilitation / Association of Academic Physiatrists, 7, (94), 530-8.

PDGF-BB inhibits intervertebral disc cell apoptosis in vitro. Presciutti, Steven M; Paglia, David N; Karukonda, Teja; Soung, Do Yu; Guzzo, Rosa; Drissi, Hicham; Moss, Isaac L. (2014). Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 9, (32), 1181-8.